Non ho trovato la fonte, ma un articolo qui https://www.galileonet.it/astrociti-comunicano/ e l’abstract dell’articolo https://onlinelibrary.wiley.com/doi/pdf/10.1002/adhm.201801139, che riporto sotto. Si tratta quindi di un “sottosistema” o “network” cooperante con quello dei neuroni? Abstract Organic bioelectronics have a huge potential to generate interfaces and devices for the study of brain functions and for the therapy of brain pathologies. In this context, increasing efforts are needed to develop technologies for monitoring and stimulation of nonexcitable brain cells, called astrocytes. Astroglial calcium signaling plays, indeed, a pivotal role in the physiology and pathophysiology of the brain. Here, the use of transparent organic cell stimulating and sensing transistor (O‐CST) architecture, fabricated with N,N′‐ditridecylperylene‐3,4,9,10‐tetracarboxylic diimide (P13), to elicit and monitor intracellular calcium concentration ([Ca2+]i) in primary rat neocortical astrocytes is demonstrated. The transparency of O‐CST allows performing calcium imaging experiments, showing that extracellular electrical stimulation of astrocytes induces a drastic increase in [Ca2+]i. Pharmacological studies indicate that transient receptor potential (TRP) superfamily are critical mediators of the [Ca2+]i increase. Experimental and computational analyses show that [Ca2+]i response is enabled by the O‐CST device architecture. Noteworthy, the extracellular field application induces a slight but significant increase in the cell volume. Collectively, it is shown that the O‐CST is capable of selectively evoking astrocytes [Ca2+]i, paving the way to the development of organic bioelectronic devices as glial interfaces to excite and control physiology of non‐neuronal brain cells. Da: autismo-biologia <[email protected]> Per conto di Fondazione Marino Inviato: domenica 3 marzo 2019 10:04 A: autismo-biologia <[email protected]> Oggetto: [autismo-biologia] Astrociti Invito a leggere un articolo su "la lettura" di oggi a firma di Valentina Benfenati. In un certo senso rivoluziona la visione neuro centrica delle funzioni cerebrali. Questi astrociti agiscono sulla memoria e sull'apprendimento e sono regolsti da "segnali di calcio " molto facilmente manipolabili. Insomma, un altro tassello sulla conoscenza del cervello che ci potrà aiutare. Buona lettura Giovanni Marino --- Questa e-mail è stata controllata per individuare virus con Avast antivirus. https://www.avast.com/antivirus